ADRC Pilot Grant Projects | ADRC 5-Year Funded Projects | Collaborative Research | Research Archives |
The Massachusetts ADRC has an extensive repository of resources that may be utilized to facilitate national and international collaborative research. We affirm the National Institutes of Health’s statement on data sharing (NOT-OD-03-032) in translating research findings into knowledge, products and procedures that will improve individual and public health.
All requests should be emailed to our Center Director, Bradley T. Hyman, MD, PhD (b_hyman@helix.mgh.harvard.edu), and should include a complete project proposal plan, documentation of human and/or animal studies protocol approvals from your local Institutional Review Board (IRB), and IRB-approved informed-consent forms (where applicable). Procedures for safeguarding data privacy, retention and disposal must be documented.
Requests for accessing and use of the Center’s resources are reviewed by the Massachusetts ADRC Executive Committee on the basis of project scientific merit and the availability of Center resources.
ADRC Pilot Grant Projects
Year 2006 Pilot Grant Recipients
The Massachusetts ADRC congratulates the following year 2006 pilot grant recipients:
Investigator:
Institution:
Project Title:Bradford C. Dickerson, MD
Massachusetts General Hospital/Harvard Medical School
High-resolution MRI of brain function and structure in aging and MCI: A pilot study
Investigator:
Institution:
Project Title:Stephen N. Gomperts, MD, PhD
Massachusetts General Hospital/Harvard Medical School
Amyloid and dopamine transporter imaging in Parkinson’s disease and Parkinson’s disease dementia
Investigator:
Institution:
Project Title:Sharon K. Inouye, MD, MPH
Aging Brain Center, Hebrew SeniorLife/Harvard Medical School
The impact of delirium on cognitive decline in Alzheimer’s diseaseYear 2005 Pilot Grant Recipients
The Massachusetts ADRC congratulates the following year 2005 pilot grant recipients:
Investigator:
Institution:
Project Title:Oksana Berezovska, Ph.D.
Massachusetts General Hospital/Harvard Medical School
FAD APP mutations and molecular neuropathology
Investigator:
Institution:
Project Title:Dan Frenkel, Ph.D.
Brigham and Women’s Hospital/Harvard Medical School
Antibody independent mucosal vaccination in AD mice
Investigator:
Institution:
Project Title:T. Matthew Townsend, Ph.D.
Brigham and Women’s Hospital/Harvard Medical School
Signaling mechanisms underlying A-beta mediated inhibition of synaptic plasticityYear 2004 Pilot Grant Recipients
The Massachusetts ADRC congratulates the following year 2004 pilot grant recipients:
Investigator:
Institution:
Project Title:Alireza Atri, M.D., Ph.D.
Massachusetts General Hospital/Harvard Medical School
Characteristics of cerebral amyloid angiopathy and leukoaraiosis in Alzheimer's disease and dementias
Investigator:
Institution:
Project Title:Ippolita Cantuti-Castelvetri, Ph.D.
Massachusetts General Hospital/Harvard Medical School
Transcriptional dysregulation in dementia with Lewy bodies
Investigator:
Institution:
Project Title:Yang Chang, M.D., Ph.D.
Massachusetts General Hospital/Harvard Medical School
FE65 proteins modulate APP processing and functionYear 2003 Pilot Grant Recipients
The Massachusetts ADRC congratulates the following year 2003 pilot grant recipients:
Investigator:
Institution:
Project Title:
Jing Bu, M.D., Ph.D.
Beth Israel Deaconess Medical Center/Harvard Medical School
Calbindin and cholinergic neurons in aging and AD
Investigator:
Institution:
Project Title:
Lee E. Goldstein, M.D., Ph.D.
Massachusetts General Hospital/Harvard Medical School
ß-amyloid deposition in Alzheimer’s disease lens
Investigator:
Institution:
Project Title:
Suzanne Y. Guenette, Ph.D.
Massachusetts General Hospital/Harvard Medical School
The insulin-degrading enzyme: It’s role in Aß and AICD degradation in vivo
Investigator:
Institution:
Project Title:
Robert D. Moir, Ph.D.
Massachusetts General Hospital/Harvard Medical School
LRP-mediated clearance of pre-fibrillar oligomeric Aß species
Year 2002 Pilot Grant Recipients
The Massachusetts ADRC congratulates the following year 2002 pilot grant recipients:
Investigator:
Institution:
Project Title:
Eun-Kyoung Choi, Ph.D.
Massachusetts General Hospital/Harvard Medical School
Functional role of calsenilin in Alzheimer's Disease
Investigator:
Institution:
Project Title:
Michael C. Irizarry, M.D.
Massachusetts General Hospital/Harvard Medical School
BACE protein and specific enzyme activity in Alzheimer's Disease brain, plasma, and CSF
Investigator:
Institution:
Project Title:
Zhongcong Xie, M.D., Ph.D.
Massachusetts General Hospital/Harvard Medical School
Effects of perioperative hypocapnia and hypoxia on cellular apoptosis contributing to Alzheimer's Disease
ADRC 5-Year Funded Projects
5 Years NIA Funded Research Projects (Years 21-25)
Investigator:
Institution:
Project Title:
Mel B. Feany, M.D., Ph.D.
Brigham and Women’s Hospital/Harvard Medical School
Phosphorylation control of tau neurotoxicity in Drosophila
Investigator:
Institution:
Project Title:
Bradley T. Hyman, M.D., Ph.D.
Massachusetts General Hospital/Harvard Medical School
Tau alterations in Alzheimer’s and related dementias5 Years NIA Funded Research Projects (Years 16-20)
Investigator:
Institution:
Project Title:
Susumu Tonegawa, Ph.D.
Massachusetts Institute of Technology
The Role of MAP Kinase in Synaptic Plasticity and Memory
Investigator:
Institution:
Project Title:
Bradley T. Hyman, M.D., Ph.D.
Massachusetts General Hospital/ Harvard Medical School
ApoE and Transgenic Models of Alzheimer's disease
Investigator:
Institution:
Project Title:
Dennis J. Selkoe, M.D.
Brigham and Women's Hospital/Harvard Medical School
Mechanism and Inhibition of Native A-Beta Aggregation in Cells
Investigator:
Institution:
Project Title:
Rudolph E. Tanzi, Ph.D.
Massachusetts General Hospital/Harvard Medical School
Genetic Analysis of Alzheimer's Genes
Collaborative Research Projects
The Massachusetts ADRC is collaborating with approximately 18 Alzheimer's Disease Centers on a federally-funded and Alzheimer's Association-supported nationwide initiative to help identify genes that play a role in the development of Alzheimer's disease, and we need your help in study participation! Background information on the Alzheimer's Disease Genetics Initiative-Multiplex Family Study can be found on the website of the National Cell Repository for Alzheimer's Disease. Please contact our Genetics Initiative Coordinator at 617-726-0970 for opportunities to partake in our national efforts to find a cure for Alzheimer's disease!
| website feedback: neurotech@partners.org | MGH Neurology |
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