May 10, 2020
I lost my mother at about this time last year, after her 10-year struggle with Alzheimer's disease. During this past year, kind friends have checked in at holidays and birthdays, understandably assuming these first landmark occasions without my mom would be difficult. The truth is something that I was at first ashamed to admit, let alone articulate: Grieving her nonw, when the loss is complete, feels nothing like I had expected. It feels easy.
April 11, 2020
MGH News (April 11, 2020): Mass General Team Detects Alzheimer’s Early Using Electronic Health Records
A team of scientists from Massachusetts General Hospital (MGH) has developed a software-based method of scanning electronic health records (EHRs) to estimate the risk that a healthy person will receive a dementia diagnosis in the future
April 9, 2020
The first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial support the hypothesis that higher brain amyloid levels represent an early preclinical stage of Alzheimer's disease (AD).
April 8, 2020
As the cornovirus advances, it is taking a particularly harsh toll on the many who are caring for for a loved one with dementia or Alzheimer's, the most common form of dementia. According to a report by the Alzheimer's Association, more than 16 million Americans are providing unpaid care for those with Alzheimer's or other types of dementia. For them, the virus is "really a double whammy," said Lynn Feinberg, a senior strategic policy AARP Public Policy Institute. "You're worrying about your own health and that of your family member".
March 26, 2020
March 9, 2020
Functional neurological disorder (FND), also known as conversion disorder, is receiving renewed attention now that certain physical signs have been validated as being specific for the diagnosis. The improved diagnostic specificity has encouraged clinician-scientists to study the neurobiology of FND with the hope of developing better treatments.
March 9, 2020
MGH News (February 28, 2020): Case of Resistance to Autosomal Dominant Alzheimer's Disease Suggests New Direction for Treatment
February 10, 2020
The beta-amyloid hypothesis has dominated Alzheimer's disease research for nearly 35 years. It proposes that plaques, comprised of the protein beta-amyloid, destroy synapses and stimulate the development of neurofibrillary tangles of the tau protein, which kills neurons in patients with the disease. Resultantly, neuroinflammation is triggered, which destroys more neurons and ultimately leads to dementia.
December 10, 2019
MGH News (November 7, 2019): "Crosstalk" Between Genes Promotes Brain Inflammation in Alzheimer's Disease
A new study at Massachusetts General Hospital reveals more information about how to prevent neuroinflammation, a response to the buildup of amyloid plaques that promote Alzheimer's disease (AD).
November 12, 2019
New York Times (November 4, 2019): Why Didn’t She Get Alzheimer’s? The Answer Could Hold a Key to Fighting the Disease
The woman’s genetic profile showed she would develop Alzheimer’s by the time she turned 50.
She, like thousands of her relatives, going back generations, was born with a gene mutation that causes people to begin having memory and thinking problems in their 40s and deteriorate rapidly toward death around age 60.