Alzheimer’s & Dementia: Expectations and clinical meaningfulness of randomized controlled trials – January 2023 - February 14, 2023
Alzheimer’s disease (AD) clinical trials are designed and powered to detect the impact of a therapeutic intervention, and there has been considerable discussion on what constitutes a clinically meaningful change in those receiving treatment versus placebo.
Read more...Neurology: Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women - July 28, 2021
The world is experiencing rapid aging, and the global prevalence of age-related cognitive decline and dementia is expected to rise substantially. The functional disability of cognitive decline and dementia not only impacts patients but also greatly burdens family and society. Effective treatments for dementia are still lacking, highlighting the importance of preventive strategies.
Read more...Science Daily: Artificial intelligence reveals current drugs that may help combat Alzheimer’s disease - March 4, 2021
Researchers have developed a method based on artificial intelligence that rapidly identifies currently available medications that may treat Alzheimer’s disease. The method also reveals potential …
Read more...Resident Honored For Alzheimer’s Work - November 2, 2020
Read more...5 advances in Alzheimer’s research and treatment that could make a difference - October 29, 2020
Read more...MGH Develops Software Which Predicts Dementia - July 20, 2020
A team of scientists from Massachusetts General Hospital (MGH) has developed a software-based method of scanning electronic health records (EHRs) to estimate the risk that a healthy person will receive a dementia diagnosis in the future. Their algorithm uses machine learning to first build a list of key clinical terms associated with cognitive symptoms identified ...
Read more...Losing My Mom to Alzheimer’s - July 20, 2020
I lost my mother at about this time last year, after her 10-year struggle with Alzheimer’s disease. During this past year, kind friends have checked in at holidays and birthdays, understandably assuming these first landmark occasions without my mom would be difficult. The truth is something that I was at first ashamed to admit, let ...
Read more...Cambridge Chronicle (June 30, 2020) Alzheimer’s research needs your help - July 1, 2020
The Massachusetts Alzheimer’s Disease Research Center (ADRC) is pleased to announce an opening for a two-year Clinical Fellowship in Dementia at the Massachusetts General Hospital (MGH) and related institutions beginning July 1, 2018.
The goal of the non-degree program is to introduce exceptionally-qualified individuals to the successes and demands of a clinical career in dementia and ...
Read more...Boston 25 News (June 23, 2020) Dr. Seth Gale on Research Status During COVID-19 - June 24, 2020
“In this multi-institution collaboration study, Dr. Yang and colleagues analyzed over 750 autopsied human brain samples and discovered and replicated that genetic variants in the TMEM106B and RBFOX1 genes change thousands of brain genes’ expression. The TMEM106B variant they identified was the exact same genetic variant that increases the risk of frontotemporal lobar degeneration (FTLD)-TDP-43 and ...
Read more...New York Times (May 9, 2020): Losing My Mom to Alzheimer’s, Then Finding Her Again - May 10, 2020
Our Center is proud to debut the Spring/Summer 2020 issue of our KEEP IN MIND newsletter. Do check it out!!
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