Observational Studies

• The Memory Unit and the Integrated Brain Health Clinical and Research Program at Massachusetts General Hospital (MGH) are developing an exercise and mind body program to promote physical and emotional health.

• We hope to optimize the program, based on your feedback, to better serve patients with chronic pain and memory problems.

If you are interested in participating, please click the following link to sign-up: https://rally.partners.org/study/activebrains

Are you monolingual in Spanish or Bilingual and interested in learning more about your memory? Our study is primarily focused on gaining a better understanding of cognitive function and Alzheimer's risk for older Latino adults.

Are you over 18? Have a family history of dementia, diagnosed with mild cognitive impairment, Alzheimer's disease, or a neurodegenerative disorder? In addition to the medical conditions mentioned previously, we are also looking for healthy volunteers and hope to establish a robust collection of various samples to better understand Alzheimer's disease and other neurodegenerative disorders.

Are you between the ages 65-90 and are monolingual or bilingual by speaking Spanish?

Would you like to further Alzheimer disease research by being a healthy volunteer for a neuroimaging study? We are looking for individuals between the ages 40-64 that do not have a diagnosis of Mild cognitive impairment or Alzheimer’s disease and to undergo MRI and PET scans and blood draws in a two-year study.

Are you a caregiver for a loved one or friend diagnosed with Front Temporal Dementia (FTD) or Amyotrophic lateral sclerosis/Lou Gehrig’s disease (ALS)? Does caregiving ever feel burdensome?

We want to see how your brain’s electrical activity plays a role in Alzheimer’s Disease. We will be comparing your brain’s electrical activity (using an EEG) with images of your brain (MRI and possibly a PET scan).

Have you been diagnosed with Mild Cognitive Impairment and are between the ages of 55 and 90? We are using phone/computer based tests that can potentially aid clinicians ability to make earlier diagnoses of Alzheimer's disease. If this sounds interesting, please review the study flyer below!

Are you interested in understanding how sleep variations are related to tau and amyloid build-up in the brain?

Have you experienced and self-reported frequent memory loss or confusion to your doctor in the past 12 months but have not been diagnosed with mild cognitive impairment or dementia? If so, you may be eligible for this research study. Participants with subjective cognitive decline complaints from community and memory disorders clinics will complete quarterly at home assessments alongside different imaging.