Observational Studies

Are you between the ages of 70 and 90 and have depressive symptoms? This observational study is being carried out to determine whether the presence or absence of late onset depressive symptoms in older adults predicts more rapid Alzheimer’s Disease (AD) associated brain related changes and AD associated cognitive decline.



Are you over 18? Have a family history of dementia, diagnosed with mild cognitive impairment, Alzheimer's disease, or a neurodegenerative disorder? In addition to the medical conditions mentioned previously, we are also looking for healthy volunteers and hope to establish a robust collection of various samples to better understand Alzheimer's disease and other neurodegenerative disorders.

Are you monolingual in Spanish or Bilingual and interested in learning more about your memory? Our study is primarily focused on gaining a better understanding of cognitive function and Alzheimer's risk for older Latino adults.

Are you between the ages 65-90 and are monolingual or bilingual by speaking Spanish?

Are you a caregiver for a loved one or friend diagnosed with Front Temporal Dementia (FTD) or Amyotrophic lateral sclerosis/Lou Gehrig’s disease (ALS)? Does caregiving ever feel burdensome?

Would you like to further Alzheimer disease research by being a healthy volunteer for a neuroimaging study? We are looking for individuals younger than 65 with mild cognitive impairment (MCI) or dementia of mild severity suspected to be caused by Alzheimer’s disease can sign up. In addition, the study is seeking a small number of individuals younger than 65 who do not have any cognitive impairment. Participants will perform study activities at the beginning of their involvement, at the mid-point one year later, and finally two years later, for a total of three visits.

We want to see how your brain’s electrical activity plays a role in Alzheimer’s Disease. We will be comparing your brain’s electrical activity (using an EEG) with images of your brain (MRI and possibly a PET scan).

Have you been diagnosed with Mild Cognitive Impairment and are between the ages of 55 and 90? We are using phone/computer based tests that can potentially aid clinicians ability to make earlier diagnoses of Alzheimer's disease. If this sounds interesting, please review the study flyer below!

Are you interested in understanding how sleep variations are related to tau and amyloid build-up in the brain?

Have you experienced and self-reported frequent memory loss or confusion to your doctor in the past 12 months but have not been diagnosed with mild cognitive impairment or dementia? If so, you may be eligible for this research study. Participants with subjective cognitive decline complaints from community and memory disorders clinics will complete quarterly at home assessments alongside different imaging.