AHEAD (A3/A45) A preventative clinical trial aimed recruiting cognitively normal individuals with a positive amyloid status to assess the effectiveness of an investigational medication BAN2401 on individuals with both intermediate and elevated levels of amyloid.
Contact: (617) 278-0600.                                                                  
Additional information: www.studymemory.org 
Location:  60 Fenwood Road, Boston, MA

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

WALLe: This study searches for individuals between 60-85 years. In our study, we examine the effect of a non-invasive electrical brain stimulation method called RAVANS on memory.
Contact: wallestudy@mgh.harvard.edu
Additional Information: https://rally.massgeneralbrigham.org/study/walle_study

BIONIC: Patients at the MGH Memory Disorders Unit will have the opportunity to complete a 30-45 minutes visit completing questionnaires and a blood draw. They will have the optional to return for longitudinal follow up once a year at the time of their clinic appointment.
Contact: Shadia Farah, sfarah5@mgh.harvard.edu 

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study Flyer

Chronic Stress as a Risk Factor for Age-Related Cognitive Decline in Latinos The overall goal of this study is to assess the impact of chronic stress, measured via paper-pencil questionnaires and a hair sample, on memory and thinking in Latino and Non-Latino adults with and without cognitive concerns
Contact: Alex Badillo-Cabrera, abadillocabrera@mgh.harvard.edu
Additional information: https://rally.massgeneralbrigham.org/study/memory_stress
Location: MGH Multicultural Alzheimer’s Prevention Program

APT Web study: Participants who are 50 years of age or older can take on-line 30-minute memory assessments every three months while researchers track their progress and contact them about new research studies available.
www.aptwebstudy.org

Instrumental Activities of Daily Living (IADL) – A study that requires you to complete assessments that can may help clinicians make an early diagnosis of AD and monitor any change in daily functioning.
Contact: Onyinye Udeogu, oudeogu@mgh.harvard.edu
Additional information: https://rally.partners.org/study/study_iadl
Location: 149 13^th Street, Charlestown, MA

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to tau and amyloid build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu or Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: robregongarcia@mgh.harvard.edu
Additional Information: Spanish Memory & Aging Study Flyer

Chronic Stress as a Risk Factor for Age-Related Cognitive Decline in Latinos The overall goal of this study is to assess the impact of chronic stress, measured via paper-pencil questionnaires and a hair sample, on memory and thinking in Latino and Non-Latino adults with and without cognitive concerns.
Contact: Alex Badillo-Cabrera, abadillocabrera@mgh.harvard.edu
Additional information:    Stress Study_Spanish Flyer                                                                                                          Location: MGH Multicultural Alzheimer’s Prevention Program

Boston Latino Aging Study (BLAST) A study to assess Spanish speaking participants cognitive function and recruit potential participants for other studies.
Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
Additional Information: BLAST Flyer Spanish
Location: 149 13^th Street, Charlestown, MA

Latino Harvard Aging Brain Study (HABS) A study that uses multiple imaging techniques to study the structure and function of the brain and to detect the presence of amyloid.
Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
Additional information: https://rally.partners.org/study/_latino_habs
Location: 149 13^th Street, Charlestown, MA

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study Flyer 

Subjective Cognitive Decline (SCD) A study that asks participants with subjective complaints complete at home assessments and have neuroimaging testing.
Contact: Alexa Coussole (617) 726-3086
Additional information: https://rally.partners.org/study/study_scd.
Click here for study flyer.
Location: 149 13^th Street, Charlestown, MA

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to tau and amyloid build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu or
Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

BIONIC: Patients at the MGH Memory Disorders Unit will have the opportunity to complete a 30-45 minutes visit completing questionnaires and a blood draw. They will have the optional to return for longitudinal follow up once a year at the time of their clinic appointment.
Contact: Shadia Farah, sfarah5@mgh.harvard.edu 

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study Flye

Chronic Stress as a Risk Factor for Age-Related Cognitive Decline in Latinos The overall goal of this study is to assess the impact of chronic stress, measured via paper-pencil questionnaires and a hair sample, on memory and thinking in Latino and Non-Latino adults with and without cognitive concerns
Contact: Alex Badillo-Cabrera, abadillocabrera@mgh.harvard.edu
Additional information: https://rally.massgeneralbrigham.org/study/memory_stress
Location: MGH Multicultural Alzheimer’s Prevention Program

Instrumental Activities of Daily Living (IADL) – A study that requires you to complete assessments that can may help clinicians make an early diagnosis of Alzheimer’s disease and monitor any change in daily functioning.
Contact: Onyinye Udeogu, oudeogu@mgh.harvard.edu
Additional information: https://rally.partners.org/study/study_iadl
Location:149 13^th Street, Charlestown, MA

Sleep on Neural Networks in Brain Aging (SONNET) – A Study to help us understand how individual variations in sleep are related to proteins (tau and amyloid) build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu  or
Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

Multimodal investigation of hyperexcitability in Alzheimer’s disease – A study looking at hyperexcitability in AD by analyzing EEG (electroencephalogram-a test used to evaluate the electrical activity in the brain) data.
Contact: Kyle Pellerin (508-320-6870)  kyle.pellerin@mgh.harvard.edu
Additional information multimodal brochure
Location: 149 13^th Street, Charlestown, MA

Trap-AD Study-Neuroimaging Research Study of Light Therapy in Mild Cognitive Impairment: The aim of this study is to better understand the effects of transcranial photobiomodulation (tPBM) on blood flow in the brain of individuals diagnosed with mild cognitive impairment, ages 65-85
Contact: pbm@mgh.harvard.edu
Additional Information: https://rally.partners.org/study/trapad_study

Memory & Aging Cohort Study (MAC) – Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

GAMMA -The main purpose of this study is to explore the effects and safety of 2-4 weeks of brain stimulation, to see if the stimulation can affect brain activity to decrease the amount of amyloid-beta and tau (proteins that build up in the brain that may contribute to memory problems) in people with MCI and AD.
Contact: Stacey Monsell, smonsell@bidmc.harvard.edu
Additional Information: Study Flyer

Lightwave – Sage Therapeutics – This 20 week, double-blind study, will look at the effects of SAGE-718 on memory and cognition via NMDAR modulation. We are looking for Individuals between the ages of 50-80 who have been previously diagnosed with MCI and/or Mild Dementia due to Alzheimer’s and who are not taking Namenda/Memantine to participate.
Contact: kdevitte-mckee@mgb.org  or 617-643-7945

Brain Monitoring Study – This study will test and optimize our device for use in older adults with Alzheimer’s disease. The new information collected from our device will help us better understand how the brain changes with the development of Alzheimer’s disease.
Contact: Jian Shi  jshi16@mgh.harvard.edu or (617) 724-9608
Additional Information: https://rally.massgeneralbrigham.org/study/ad_brain_eval

WALLe: This study searches for individuals between 60-85 years. In our study, we examine the effect of a non-invasive electrical brain stimulation method called RAVANS on memory.
Contact: wallestudy@mgh.harvard.edu
Additional Information: https://rally.massgeneralbrigham.org/study/walle_study

BIONIC: Patients at the MGH Memory Disorders Unit will have the opportunity to complete a 30-45 minutes visit completing questionnaires and a blood draw. They will have the optional to return for longitudinal follow up once a year at the time of their clinic appointment.
Contact: Shadia Farah, sfarah5@mgh.harvard.edu 

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study Flyer

Chronic Stress as a Risk Factor for Age-Related Cognitive Decline in Latinos The overall goal of this study is to assess the impact of chronic stress, measured via paper-pencil questionnaires and a hair sample, on memory and thinking in Latino and Non-Latino adults with and without cognitive concerns
Contact: Alex Badillo-Cabrera, abadillocabrera@mgh.harvard.edu
Location: MGH Multicultural Alzheimer’s Prevention Program

APT Web study: Participants who are 50 years of age or older can take on-line 30-minute memory assessments every three months while researchers track their progress and contact them about new research studies available.
www.aptwebstudy.org

Instrumental Activities of Daily Living (IADL) – A study that requires you to complete assessments that can may help clinicians make an early diagnosis of AD and monitor any change in daily functioning.
Contact: Onyinye Udeogu, oudeogu@mgh.harvard.edu
Additional information: https://rally.partners.org/study/study_iadl
Location: 149 13^th Street, Charlestown, MA

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to tau and amyloid build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu or Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

NMN AD Study– Men and women aged 55-85 who are diagnosed with mild Alzheimer’s disease are invited to join our study which is investigating whether study drug MIB-626 can  be beneficial for Alzheimer’s patients.
Contact: Bella Levesque, ilevesque@bwh.harvard.edu
Additional Information: Study Flyer
Location: 60 Fenwood Road Boston, MA 02115                                             

Memory Awareness AWARE –A study investigating how assessing one’s own memory performance changes in normal aging and in people diagnosed with Mild Cognitive Impairment or Alzheimer’s Disease.
Contact: Alexa Coussole, acoussoule@bwh.harvard.edu
More information: https://rally.partners.org/study/the_memoryawareness_study
Location: 149 13^th Street, Charlestown, MA

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to proteins (tau and amyloid) build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu
Additional information:  https://rally.partners.org/study/sonnet
Location: 149 13th Street, Charlestown, MA

Multimodal investigation of hyperexcitability in Alzheimer’s disease – A study looking at hyperexcitability in individuals with dementia from probable Alzheimer’s Disease or Mild Cognitive Impairment. Participants will have a 12-hour overnight EEG (electroencephalogram a test used to evaluate the electrical activity in the brain) at their home.
Contact: Kyle Pellerin (508-320-6870)  kyle.pellerin@mgh.harvard.edu
Additional information Multimodal brochure
Location: 149 13^th Street, Charlestown, MA

Tau PET Imaging Study A Longitudinal study of participants with primary progressive aphasia, posterior cortical atrophy, or Alzheimer’s disease to evaluate using Tau imaging.
Contact: Sophia Tchir STCHIR@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Longitudinal Early Onset Disease Study (LEADS)– A study to compare biomarker data of cognitively impaired (Early Onset Alzheimer’s Disease and non-Early Onset Alzheimer’ Disease) and Clinically Normal to Longitudinal Alzheimer’s Disease participants.
Contact: Inola Howe IAHOWE@mgh.harvard.edu
Additional information: LEADS flyer
Location: 149 13^th Street, Charlestown, MA

Memory & Aging Cohort Study (MAC) – Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

Envision  – This study will look at whether an investigational drug (Aducanumab), is beneficial to help slow or stop memory loss in people experiencing early stages of Alzheimer’s disease.
Contact: Jennifer Ramirez jramirez@pcpo.partners.org  (617) 525-3666
Additional Information: https://rally.massgeneralbrigham.org/study/envision

Lightwave – Sage Therapeutics – This 20 week, double-blind study, will look at the effects of SAGE-718 on memory and cognition via NMDAR modulation. We are looking for Individuals between the ages of 50-80 who have been previously diagnosed with MCI and/or Mild Dementia due to Alzheimer’s and who are not taking Namenda/Memantine to participate.
Contact: kdevitte-mckee@mgb.org  or 617-643-7945

Brain Monitoring Study – This study will test and optimize our device for use in older adults with Alzheimer’s disease. The new information collected from our device will help us better understand how the brain changes with the development of Alzheimer’s disease.
Contact: Jian Shi  jshi16@mgh.harvard.edu or (617) 724-9608
Additional Information: https://rally.massgeneralbrigham.org/study/ad_brain_eval

GIFTED This study explores the safety, tolerability, and effectiveness of 6 weeks of daily transcranial alternating current stimulation (tACS) in people with behavioral variant frontotemporal dementia (bvFTD). Cognitive testing, MRI scans, PET scans, and blood draws are used.   
Contact: Julianne Reilly, jrreilly@mgh.harvard.edu
Additional information: https://rally.massgeneralbrigham.org/study/gifted

LRTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) A longitudinal study of participants with diagnosis of FTD, symptoms of FTD or, who have a strong family history of FTD.                      
Contact: Erin Krahn, ekrahn@mgh.harvard.edu

Tau PET Imaging Study -A Longitudinal study of participants with primary progressive aphasia, posterior cortical atrophy, or Alzheimer’s disease to evaluate using Tau imaging.
Contact: Sophia Tchir STCHIR@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA 

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) A longitudinal study of participants with diagnosis of FTD, symptoms of FTD or, who have a strong family history of FTD.                      
Contact: Erin Krahn, ekrahn@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Tau PET Imaging Study -A Longitudinal study of participants with primary progressive aphasia, posterior cortical atrophy, or Alzheimer’s disease to evaluate using Tau imaging.
Contact:Sophia Tchir  STCHIR@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA 

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) A longitudinal study of participants with diagnosis of FTD, symptoms of FTD or, who have a strong family history of FTD.                      
Contact: Erin Krahn, ekrahn@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) A longitudinal study of participants with diagnosis of FTD, symptoms of FTD or, who have a strong family history of FTD.                      
Contact: Erin Krahn, ekrahn@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

4-Repeat Tauopathy Neuroimaging Initiative, Cycle 2 Study (4RTNI-2) This study monitors the process of multiple brain disorders using imaging, bodily fluids, and cognitive testing in participants with progressive supranuclear palsy or corticobasal syndrome.
Contact: Gent Celaj GCELAJ@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Investigation of Epigenetic Mechanisms in Parkinson’s Disease and dementia with Lewy bodies patients Quantified by Non-Invasive PET Imaging – This study is looking at master regulators of gene expression in the brain in dementia with Lewy bodies (DLB) and Parkinson’s disease.
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

Web-Based Automated Imaging Differentiation of Parkinsonism – This study is testing an MRI strategy to improve the diagnosis of Parkinson’s disease, progressive supranuclear palsy (PSP), and multiple systems atrophy (MSA).
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

Investigation of Epigenetic Mechanisms in Parkinson’s Disease and dementia with Lewy bodies patients Quantified by Non-Invasive PET Imaging – This study is looking at master regulators of gene expression in the brain in dementia with Lewy bodies (DLB) and Parkinson’s disease.
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

Web-Based Automated Imaging Differentiation of Parkinsonism – This study is testing an MRI strategy to improve the diagnosis of Parkinson’s disease, progressive supranuclear palsy (PSP), and multiple systems atrophy (MSA).
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

• Vascular Pathology in Early and Asymptomatic Cerebral Angiopathy –This study aims to identify signature markers through MRIs and memory/attention testing to learn more about the progression of both Cerebral Amyloid Angiopathy and memory loss.
  Contact: Vanessa Gonzalez vagonzalez@mgh.harvard.edu
  Additional information: https://rally.partners.org/study/caamemorystudy
  Location: Mass General Hospital

• Boston Latino Aging Study (BLAST) A study to assess Spanish speaking participants cognitive function and recruit potential participants for other studies.
  Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
  Additional Information: BLAST Flyer Spanish
  Location: 149 13^th Street, Charlestown, MA
•  
• Latino Harvard Aging Brain Study (HABS) A study that uses multiple imaging techniques to study the structure and function of the brain and to detect the presence of amyloid.
  Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
  Additional information: https://rally.partners.org/study/_latino_habs
  Location: 149 13^th Street, Charlestown, MA

• Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
  Contact: MemoryAndAging@mgh.harvard.edu                                                                  Additional Information: MAC Study flyers
  English: rally.massgeneralbrigham.org/study/memoryandagingcohort
  Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

• MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.                                                                              
  Contact: robregongarcia@mgh.harvard.edu                                                               
  Additional Information: Spanish Memory & Aging Study

STRIDE Study – The purpose of the study is to explore how mobile health applications impact stress levels in dementia caregivers.
Contact:  MGHSTRIDEstudy@partners.org
Additional Information: STRIDE Flyer

Northeastern University Music-Based Intervention Research Study
MBI Flyer 
https://web.northeastern.edu/mindlab/
Contact: mindlabwes@gmail.com 

McLean Hospital
Contact: Stefanie WONG SWONG18@PARTNERS.ORG 

Beth Israel Deaconess Medical Center:
GAMMA -The main purpose of this study is to explore the effects and safety of 2-4 weeks of brain stimulation, to see if the stimulation can affect brain activity to decrease the amount of amyloid-beta and tau (proteins that build up in the brain that may contribute to memory problems) in people with MCI and AD.
Contact: Stacey Monsell, smonsell@bidmc.harvard.edu

AHEAD (A3/A45) A preventative clinical trial aimed recruiting cognitively normal individuals with a positive amyloid status to assess the effectiveness of an investigational medication BAN2401 on individuals with both intermediate and elevated levels of amyloid.
Contact: 617-278-0600
Additional information: : https://www.aheadstudy.org
Location:  60 Fenwood Road, Boston, MA

Check back soon!

Trap-AD Study-Neuroimaging Research Study of Light Therapy in Mild Cognitive Impairment: The aim of this study is to better understand the effects of transcranial photobiomodulation (tPBM) on blood flow in the brain of individuals diagnosed with mild cognitive impairment, ages 65-85
Contact: pbm@mgh.harvard.edu
Additional Information: https://rally.partners.org/study/trapad_study 

GAMMA -The main purpose of this study is to explore the effects and safety of 2-4 weeks of brain stimulation, to see if the stimulation can affect brain activity to decrease the amount of amyloid-beta and tau (proteins that build up in the brain that may contribute to memory problems) in people with MCI and AD.
Contact: Stacey Monsell, smonsell@bidmc.harvard.edu
Additional Information: Study Flyer

BCG vaccine -BCG vaccine is thought to have “off target” effects in the immune system, specifically on T regulatory cells which maintain homesostasis of the immune response. This vaccine has been given to billions of people worldwide, as Japan BCG is used by UNICEF and WHO as the standard tuberculosis vaccination.                                                      Contact: Kate Cropp, KCROPP1@mgh.harvard.edu  617-643-4802
Additional Information: https://rally.massgeneralbrigham.org/study/bcg_in_ad Location: 149 13th Street, Charlestown, MA   

Envision  – This study will look at whether an investigational drug (Aducanumab), is beneficial to help slow or stop memory loss in people experiencing early stages of Alzheimer’s disease.
Contact: Jennifer Ramirez jramirez@pcpo.partners.org   (617) 525-3666
Additional Information: https://rally.massgeneralbrigham.org/study/envision

GIFTED This study explores the safety, tolerability, and effectiveness of 6 weeks of daily transcranial alternating current stimulation (tACS) in people with behavioral variant frontotemporal dementia (bvFTD). Cognitive testing, MRI scans, PET scans, and blood draws are used.                      
Contact: Hannah Bedrosian HBEDROSIAN@mgh.harvard.edu

Transcranial Magnetic Stimulation Study -This study evaluates use of repetitive transcranial magnetic stimulation to target areas of memory and language in patients with amnestic mild cognitive impairment and the logogenic or non-fluent variant of primary progressive aphasia.
Contact: Gent Celaj GCELAJ@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Northeastern University Music-Based Intervention Research Study
MBI Flyer 
https://web.northeastern.edu/mindlab/
Contact: mindlabwes@gmail.com

McLean Hospital
Contact: Stefanie Wong SWONG18@PARTNERS.ORG

Beth Israel Deaconess Medical Center

GAMMA -The main purpose of this study is to explore the effects and safety of 2-4 weeks of brain stimulation, to see if the stimulation can affect brain activity to decrease the amount of amyloid-beta and tau (proteins that build up in the brain that may contribute to memory problems) in people with MCI and AD.

Contact: Stacey Monsell, smonsell@bidmc.harvard.edu

BIONIC: Patients at the MGH Memory Disorders Unit will have the opportunity to complete a 30-45 minutes visit completing questionnaires and a blood draw. They will have the optional to return for longitudinal follow up once a year at the time of their clinic appointment.                                                                                                            
Contact: Shadia Farah, sfarah5@mgh.harvard.edu 

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study  Flyer

APT Web study: Participants who are 50 years of age or older can take on-line 30-minute memory assessments every three months while researchers track their progress and contact them about new research studies available.
Additional Information:  www.aptwebstudy.org

Instrumental Activities of Daily Living (IADL) – A study that requires you to complete assessments that can may help clinicians make an early diagnosis of AD and monitor any change in daily functioning.                                                       
Contact: Onyinye Udeogu, oudeogu@mgh.harvard.edu
Additional information: https://rally.partners.org/study/study_iadl
Location: 149 13^th Street, Charlestown, MA

Alzheimer’s Disease EEG Sleep Study–   A study to look at disrupted sleep dynamics and altered sleep oscillations to better understand the relationship between sleep and aging and Alzheimer’s disease in cognitively normal, Mild Cognitive Impairment and Alzheimer’s disease. This study will evaluate resting state EEG (electroencephalogram-a test used to evaluate the electrical activity in the brain) and PET/ MRI imaging biomarkers to better understand markers for preclinical and prodromal AD.
Contact: purdonlab@mgh.harvard.edu
Additional information: https://rally.partners.org/study/noninvasive_biomarkers
Location: 149 13^th Street, Charlestown, MA 

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu. 
Additional Information: MAC Study flyers 
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es                                                                                                

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to tau and amyloid build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu or Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet                         
Location:149 13^th Street, Charlestown, MA

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: robregongarcia@mgh.harvard.edu
Additional Information: Spanish Memory & Aging Study

Boston Latino Aging Study (BLAST) A study to assess Spanish speaking participants cognitive function and recruit potential participants for other studies.
Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
Additional Information: BLAST Flyer Spanish
Location: 149 13^th Street, Charlestown, MA

Latino Harvard Aging Brain Study (HABS) A study that uses multiple imaging techniques to study the structure and function of the brain and to detect the presence of amyloid.
Contact: Alex Badillo Cabrera, abadillocabrera@mgh.harvard.edu
Additional information: https://rally.partners.org/study/_latino_habs
Location: 149 13^th Street, Charlestown, MA

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study  Flyer

Subjective Cognitive Decline (SCD) A study that asks participants with subjective complaints complete at home assessments and have neuroimaging testing.
Contact: Alexa Coussole (617) 726-3086
Additional information: https://rally.partners.org/study/study_scd
Click here for study flyer
Location: 149 13^th Street, Charlestown, MA.   

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to tau and amyloid build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu  or Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

 BIONIC: Patients at the MGH Memory Disorders Unit will have the opportunity to complete a 30-45 minutes visit completing questionnaires and a blood draw. They will have the optional to return for longitudinal follow up once a year at the time of their clinic appointment.
Contact: Shadia Farah, sfarah5@mgh.harvard.edu 

MADRC Memory & Aging Study: An observational study for participants 50 years old and over with or without memory loss/dementia. The study consists of a yearly visit with a doctor to complete memory testing. The goal is to gather long-term data to help better understand the aging brain.
Contact: JJOHANSON1@mgh.harvard.edu
Additional Information: Memory & Aging Study  Flyer

Instrumental Activities of Daily Living (IADL) – A study that requires you to complete assessments that can may help clinicians make an early diagnosis of Alzheimer’s disease and monitor any change in daily functioning.
Contact: Onyinye Udeogu, oudeogu@mgh.harvard.edu
Additional information: https://rally.partners.org/study/study_iadl
Location: 149 13^th Street, Charlestown, MA

Sleep on Neural Networks in Brain Aging (SONNET) –A Study to help us understand how individual variations in sleep are related to proteins (tau and amyloid) build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu or Raina Levin, rlevin4@mgh.harvard.edu
Additional information: https://rally.partners.org/study/sonnet
Location:149 13^th Street, Charlestown, MA

Multimodal investigation of hyperexcitability in Alzheimer’s disease – A study looking at hyperexcitability in AD by analyzing EEG (electroencephalogram-a test used to evaluate the electrical activity in the brain) data.
Contact: Kyle Pellerin(508-320-6870)    kyle.pellerin@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Alzheimer’s Disease EEG Sleep Study–   A study to look at pre -clinical diagnosis and longitudinal tracking of Alzheimer’s Disease using Sleep and Resting State EEG (electroencephalogram-a test used to evaluate the electrical activity in the brain).
Contact: purdonlab@mgh.harvard.edu
Additional information: https://rally.partners.org/study/risk_of_alzheimers
Location: 149 13^th Street, Charlestown, MA     

Memory Awareness – A study investigating how assessing one’s own memory performance changes in normal aging and in people diagnosed with Mild Cognitive Impairment or Alzheimer’s Disease.
Contact: Alexa Coussole, acoussoule@bwh.harvard.edu
Additional info: https://rally.partners.org/study/the_memoryawareness_study.  
Location: 149 13^th Street, Charlestown, MA

Sleep on Neural Networks in Brain Aging (SONNET) – A study to help us understand how individual variations in sleep are related to proteins (tau and amyloid) build-up in the brain.
Contact: Valentina Paz Pinilla, VPINILLA@mgh.harvard.edu
Additional information https://rally.partners.org/study/sonnet
Location: 149 13^th Street, Charlestown, MA

Multimodal investigation of hyperexcitability in Alzheimer’s disease – A study looking at hyperexcitability in individuals with dementia from probable Alzheimer’s Disease or Mild Cognitive Impairment. Participants will have a 12-hour overnight EEG (electroencephalogram a test used to evaluate the electrical activity in the brain) at their home.
Contact: Kyle Pellerin (508-320-6870 )  kyle.pellerin@mgh.harvard.edu
Additional information: Multimodal flyer
Location: 149 13^th Street, Charlestown, MA

Tau PET Imaging Study – A Longitudinal study of participants with primary progressive aphasia, posterior cortical atrophy, or Alzheimer’s disease to evaluate using Tau imaging.
Contact: Sophia Tchir  STCHIR@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Longitudinal Early Onset Disease Study (LEADS)– A study to compare biomarker data of cognitively impaired (Early Onset Alzheimer’s Disease and non-Early Onset Alzheimer’ Disease) and Clinically Normal to Longitudinal Alzheimer’s Disease participants.
Contact: Inola Howe IAHOWE@mgh.harvard.edu
Additional information: AA_LEADS-Brochure_
Location: 149 13^th Street, Charlestown, MA

Alzheimer’s Disease EEG Sleep Study–   A study to look at pre -clinical diagnosis and longitudinal tracking of Alzheimer’s Disease using Sleep and Resting State EEG (electroencephalogram-a test used to evaluate the electrical activity in the brain).
Contact: purdonlab@mgh.harvard.edu
Additional information: https://rally.partners.org/study/noninvasive_biomarkers
Location: 149 13^th Street, Charlestown, MA 

Memory & Aging Cohort Study (MAC): Participants age 45+ will complete memory tests, a blood draw and questionnaires in one study visit. This study is looking at the relationship between the substances in your blood and your memory and thinking abilities. You will be compensated $50 for this visit.
Contact: MemoryAndAging@mgh.harvard.edu
Additional Information: MAC Study flyers
English: rally.massgeneralbrigham.org/study/memoryandagingcohort
Spanish: rally.massgeneralbrigham.org/study/memoryandagingcohort?lang=es

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)– A longitudinal study of participants with diagnosis of FTD, symptoms of FTD or, who have a strong family history of FTD.
Contact: Erin Krahn, ekrahn@mgh.harvard.edu

Tau PET Imaging Study – A Longitudinal study of participants with primary progressive aphasia, posterior cortical atrophy, or Alzheimer’s disease to evaluate using Tau imaging.
Contact: Sophia Tchir STCHIR@mgh.harvard.edu
Location: 149 13^th Street, Charlestown, MA

Investigation of Epigenetic Mechanisms in Parkinson’s Disease and dementia with Lewy bodies patients Quantified by Non-Invasive PET Imaging – This study is looking at master regulators of gene expression in the brain in dementia with Lewy bodies (DLB) and Parkinson’s disease.
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

Web-Based Automated Imaging Differentiation of Parkinsonism – This study is testing an MRI strategy to improve the diagnosis of Parkinson’s disease, progressive supranuclear palsy (PSP), and multiple systems atrophy (MSA).
Contact: Anna Goodheart agoodheart@partners.org
Location: 149 13^th Street, Charlestown, MA

Vascular Pathology in Early and Asymptomatic Cerebral Angiopathy –This study aims to identify signature markers through MRIs and memory/attention testing to learn more about the progression of both Cerebral Amyloid Angiopathy and memory loss.
Contact: Vanessa Gonzalez vagonzalez@mgh.harvard.edu
Additional information: https://rally.partners.org/study/caamemorystudy
Location: Mass General Hospital

Care Planning for a Loved One with Dementia: Knowledge, Preparing for Decisions, and Emotions – The purpose of this study is to learn more about medical decision-making needs for patients and caregivers with ADRD (Alzheimer’s Disease and Related Dementias).
Contact: gcelaj@mgh.harvard.edu or (617) 726-4587
Additional Information: https://rally.massgeneralbrigham.org/study/are_you_a_caregiver?code=GENLPUBLIC_05012023_MISSED_6_8

STRIDE Study – The purpose of the study is to explore how mobile health applications impact stress levels in dementia caregivers.
Contact:  MGHSTRIDEstudy@partners.org
Additional Information: STRIDE Flyer

SOCIAL (Supporting Our Caregivers in ADRD Learning) – We are asking individuals to participate in a weekly 60-minute training session for 6-weeks. These sessions will teach caregivers skills around mindfulness, self-compassion, and how to navigate their care recipient’s challenging behaviors.
impact stress levels in dementia caregivers.
Contact: atravis1@mgh.harvard.edu  or (617) 726-9623
Additional Information: https://rally.massgeneralbrigham.org/study/social

 McLean Hospital
Contact: Stefanie Wong  SWONG18@PARTNERS.ORG

Northeastern University Music-Based Intervention Research Study 
MBI Flyer
https://web.northeastern.edu/mindlab/
Contact: mindlabwes@gmail.com

Beth Israel Deaconess Medical Center
GammaR01- A 3-4 month study to explore effects and safety of non-invasive brain stimulation in participants with a diagnosis of MCI to moderate AD. Participants will undergo MRI, PET, EEG, non-invasive brain stimulation, and neurocognitive tests.